HRID956068

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID175

Acetate

C2H3O2-

2 次

HCID313

Hydrochloric Acid

ClH

HCID1140

Toluene

C7H8

HCID14268

4-Bromopyridine

C5H4BrN

HCID105144

Palladium(2+)

Pd+2

结构：c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(P(c3ccccc3)c3ccccc3)ccc3ccccc23)cc1

HCID634876

2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

C44H32P2

HCID34178604

tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate

C13H24N2O2

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC2(CCN(c3ccncc3)CC2)C1

HCID59047377

1,1-Dimethylethyl 8-(4-pyridinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate

C18H27N3O2

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8249ec5c6aa14b27bcdef89518332ed1
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:64][c:65]1[cH:66][cH:67][n:68][cH:69][cH:70]1.[CH2:47]1[N:48]([C:57](=[O:58])[O:59][C:60]([CH3:61])([CH3:62])[CH3:63])[CH2:49][CH2:50][C:51]12[CH2:52][CH2:53][NH:54][CH2:55][CH2:56]2.[CH3:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1.[ClH:71].[O-:80][C:81]([CH3:82])=[O:83].[O-:84][C:85]([CH3:86])=[O:87].[Pd+2:79].[cH:1]1[cH:2][cH:3][c:4]([P:5]([c:6]2[cH:7][cH:8][c:9]3[c:10]([cH:11][cH:12][cH:13][cH:14]3)[c:15]2-[c:16]2[c:17]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[cH:23][cH:24][c:25]2[P:26]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46]1>>[CH2:47]1[N:48]([C:57](=[O:58])[O:59][C:60]([CH3:61])([CH3:62])[CH3:63])[CH2:49][CH2:50][C:51]12[CH2:52][CH2:53][N:54]([c:65]1[cH:66][cH:67][n:68][cH:69][cH:70]1)[CH2:55][CH2:56]2