Acetate → tert-Butyl 8-(pyridin-4-yl)-2,8-diazaspiro[4,5]decane-2-carboxylate

HRID 956068Notes

Reaction equation

[Br:64][c:65]1[cH:66][cH:67][n:68][cH:69][cH:70]1.[CH2:47]1[N:48]([C:57](=[O:58])[O:59][C:60]([CH3:61])([CH3:62])[CH3:63])[CH2:49][CH2:50][C:51]12[CH2:52][CH2:53][NH:54][CH2:55][CH2:56]2.[CH3:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1.[ClH:71].[O-:80][C:81]([CH3:82])=[O:83].[O-:84][C:85]([CH3:86])=[O:87].[Pd+2:79].[cH:1]1[cH:2][cH:3][c:4]([P:5]([c:6]2[cH:7][cH:8][c:9]3[c:10]([cH:11][cH:12][cH:13][cH:14]3)[c:15]2-[c:16]2[c:17]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[cH:23][cH:24][c:25]2[P:26]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46]1>>[CH2:47]1[N:48]([C:57](=[O:58])[O:59][C:60]([CH3:61])([CH3:62])[CH3:63])[CH2:49][CH2:50][C:51]12[CH2:52][CH2:53][N:54]([c:65]1[cH:66][cH:67][n:68][cH:69][cH:70]1)[CH2:55][CH2:56]2