Tetrahydrofuran → 5-hydroxy-12-(alpha-chloroethoxycarbonyl)-12H-benzo[a]phenothiazine
Reaction equation
[Cl:20][C:21](=[O:22])[O:23][CH:24]([CH3:25])[Cl:26].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1.[OH:1][c:2]1[c:3]2[c:4]([c:5]3[c:14]([cH:15]1)[S:13][c:12]1[c:7]([cH:8][cH:9][cH:10][cH:11]1)[NH:6]3)[cH:16][cH:17][cH:18][cH:19]2>>[OH:1][c:2]1[c:3]2[c:4]([c:5]3[c:14]([cH:15]1)[S:13][c:12]1[c:7]([cH:8][cH:9][cH:10][cH:11]1)[N:6]3[C:21](=[O:22])[O:23][CH:24]([CH3:25])[Cl:26])[cH:16][cH:17][cH:18][cH:19]2Participants
4
Sources & evidence
- ORD record
- ord-7314338014cc4be7b48c4dd489921dc4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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