Triethylamine → 2-[4-[[6-Methoxy-4-methyl-5-(8-phenyloctoxy)quinolin-8-yl]amino]pentyl]isoindole-1,3-dione
Reaction equation
[Br:30][CH:31]([CH2:32][CH2:33][CH2:34][N:35]1[C:36](=[O:45])[c:37]2[c:38]([cH:41][cH:42][cH:43][cH:44]2)[C:39]1=[O:40])[CH3:46].[CH3:47][CH2:48][N:49]([CH2:50][CH3:51])[CH2:52][CH3:53].[NH2:1][c:2]1[cH:3][c:4]([O:28][CH3:29])[c:5]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:6]2[c:7]([CH3:12])[cH:8][cH:9][n:10][c:11]12>>[NH:1]([c:2]1[cH:3][c:4]([O:28][CH3:29])[c:5]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:6]2[c:7]([CH3:12])[cH:8][cH:9][n:10][c:11]12)[CH:31]([CH2:32][CH2:33][CH2:34][N:35]1[C:36](=[O:45])[c:37]2[c:38]([cH:41][cH:42][cH:43][cH:44]2)[C:39]1=[O:40])[CH3:46]Participants
4
Sources & evidence
- ORD record
- ord-b846f3f284864d5aba0cadf521d2dda2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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