Dichloromethane → Trifluoroacetic acid

HRID 956347Notes

Reaction equation

HRID 956347 reaction equation
[Cl:16][CH2:17][Cl:18].[F:19][C:20]([C:21](=[O:22])[OH:23])([F:24])[F:25].[F:1][C:2]1([F:15])[CH2:3][CH:4]([NH:7][C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:5][CH2:6]1>>[F:19][C:20]([C:21](=[O:22])[OH:23])([F:24])[F:25].[F:1][C:2]1([F:15])[CH2:3][CH:4]([NH2:7])[CH2:5][CH2:6]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 58293502Tert-butyl 3,3-difluorocyclopentylcarbamate

Product 2

HCID 6422Trifluoroacetic acidHCID 53302322HCID 53302322, compound

Sources & evidence

ORD record
ord-462b522ac1944555a1f29d44890190ae
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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