4-Toluenesulfonyl chloride → 4-methyl-N-[3-(2-phenylethynyl)-5-(trifluoromethyl)pyridin-2-yl]benzenesulfonamide
Reaction equation
[c:1]1([C:7]#[C:8][c:9]2[c:10]([NH2:19])[n:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1.[c:20]1([CH3:30])[cH:21][cH:22][c:23]([S:26](=[O:27])(=[O:28])[Cl:29])[cH:24][cH:25]1>>[c:1]1([C:7]#[C:8][c:9]2[c:10]([NH:19][S:26]([c:23]3[cH:22][cH:21][c:20]([CH3:30])[cH:25][cH:24]3)(=[O:27])=[O:28])[n:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-e98841df65a84ca3a5d0a8dff748b4bb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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