Methanol → 6-Difluoromethyl-2-(3-methoxy-propyl)-nicotinic acid
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[c:5]([CH2:13][CH2:14][CH2:15][O:16][CH3:17])[n:6][c:7]([CH:10]([F:11])[F:12])[cH:8][cH:9]1)=[O:18].[CH3:23][OH:24].[Li+:21].[OH-:20].[OH2:19].[OH2:22]>>[O:2]=[C:3]([c:4]1[c:5]([CH2:13][CH2:14][CH2:15][O:16][CH3:17])[n:6][c:7]([CH:10]([F:11])[F:12])[cH:8][cH:9]1)[OH:18]Participants
6
Sources & evidence
- ORD record
- ord-5fbc718bde4443138f2d9448e1698504
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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