Toluene → 4-Propyl-cyclohexanecarboxylic acid 3-bromo-2,2-dimethyl-propyl ester

HRID 956733Notes

Reaction equation

HRID 956733 reaction equation
[Br:13][CH2:14][C:15]([CH2:16][OH:17])([CH3:18])[CH3:19].[CH2:1]([CH2:2][CH3:3])[CH:4]1[CH2:5][CH2:6][CH:7]([C:10](=[O:11])[OH:12])[CH2:8][CH2:9]1.[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[c:20]1([CH3:21])[cH:22][cH:23][c:24]([S:25]([OH:26])(=[O:27])=[O:28])[cH:29][cH:30]1>>[CH2:1]([CH2:2][CH3:3])[CH:4]1[CH2:5][CH2:6][CH:7]([C:10]([O:11][CH2:16][C:15]([CH2:14][Br:13])([CH3:18])[CH3:19])=[O:12])[CH2:8][CH2:9]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 6101p-Toluenesulfonic acidHCID 1425013-Bromo-2,2-dimethyl-1-propanolHCID 1490324(1s,4r)-4-Propylcyclohexane-1-carboxylic acid

Product 1

HCID 592890294-Propyl-cyclohexanecarboxylic acid 3-bromo-2,2-dimethyl-propyl ester

Sources & evidence

ORD record
ord-3c900b4903a3478992bf6b81d8fb2262
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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