Ethanol → ethyl 1-(2-aminoethyl)-1H-indazole-5-carboxylate

HRID 956740Notes

Reaction equation

HRID 956740 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:35][CH2:36][OH:37].[NH2:28][NH2:29].[O:1]=[C:2]1[N:3]([CH2:12][CH2:13][n:14]2[n:15][cH:16][c:17]3[cH:18][c:19]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:20][cH:21][c:22]23)[C:10](=[O:11])[c:5]2[c:4]1[cH:9][cH:8][cH:7][cH:6]2>>[NH2:3][CH2:12][CH2:13][n:14]1[n:15][cH:16][c:17]2[cH:18][c:19]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:20][cH:21][c:22]12

Participants

5

Reactant 4

HCID 702EthanolHCID 8028Tetrahydrofuran2×HCID 9321HydrazineHCID 10832532Ethyl 1-[2-(1,3-dioxoisoindolin-2-yl)ethyl]-1H-indazole-5-carboxylate

Product 1

HCID 10585718ethyl 1-(2-aminoethyl)-1H-indazole-5-carboxylate

Sources & evidence

ORD record
ord-40aad21f36fe4999a0bbffd133abcc55
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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