Dimethylformamide → t-Butoxycarbonyl-glycyl-glycine-2,4,5-Trichlorophenyl Ester

HRID 956757Notes

Reaction equation

HRID 956757 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][C:10](=[O:11])[NH:12][CH2:13][C:14](=[O:15])[OH:16].[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[CH:35]1([N:36]=[C:37]=[N:38][CH:39]2[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]2)[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]1.[OH:17][c:18]1[cH:19][c:20]([Cl:21])[c:22]([Cl:23])[cH:24][c:25]1[Cl:26].[OH:27][N:28]1[C:29](=[O:30])[CH2:31][CH2:32][C:33]1=[O:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][C:10](=[O:11])[NH:12][CH2:13][C:14]([O:15][c:18]1[cH:19][c:20]([Cl:21])[c:22]([Cl:23])[cH:24][c:25]1[Cl:26])=[O:16]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 72712,4,5-TrichlorophenolHCID 10868DicyclohexylcarbodiimideHCID 80170N-HydroxysuccinimideHCID 3334662-(2-{[(Tert-butoxy)carbonyl]amino}acetamido)acetic acid

Product 1

HCID 54236985t-Butoxycarbonyl-glycyl-glycine-2,4,5-Trichlorophenyl Ester

Sources & evidence

ORD record
ord-67bbd39ceb654fd7918185e42e44a663
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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