Water → [3-(3-Chlorophenyl)-2,1-benzisoxazol-5-yl](4-iodophenyl)-methanone

HRID 956761Notes

Reaction equation

HRID 956761 reaction equation
[Br:6][c:7]1[cH:8][cH:9][c:10]2[c:11]([c:12](-[c:15]3[cH:16][c:17]([Cl:21])[cH:18][cH:19][cH:20]3)[o:13][n:14]2)[cH:22]1.[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[I:23][c:24]1[cH:25][cH:26][c:27]([C:28](=[O:29])[N:30]([O:31][CH3:32])[CH3:33])[cH:34][cH:35]1.[OH2:36]>>[c:7]1([C:28]([c:27]2[cH:26][cH:25][c:24]([I:23])[cH:35][cH:34]2)=[O:29])[cH:8][cH:9][c:10]2[c:11]([c:12](-[c:15]3[cH:16][c:17]([Cl:21])[cH:18][cH:19][cH:20]3)[o:13][n:14]2)[cH:22]1

Participants

6

Reactant 5

HCID 962WaterHCID 8028TetrahydrofuranHCID 54617564-Iodo-N-methoxy-N-methyl-benzamideHCID 120166705-Bromo-3-(3-chlorophenyl)-2,1-benzisoxazoleHCID 178418339Butyllithium

Product 1

HCID 21082022[3-(3-Chlorophenyl)-2,1-benzisoxazol-5-yl](4-iodophenyl)-methanone

Sources & evidence

ORD record
ord-f1f61382b4e64dc9802ed2744512eb19
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…