5-Fluorouracil → Tegafur

HRID 956882Notes

Reaction equation

HRID 956882 reaction equation
[CH2:10]1[CH2:11][CH:12]=[CH:13][O:14]1.[F:1][c:2]1[c:3](=[O:9])[nH:4][c:5](=[O:8])[nH:6][cH:7]1.[O:15]1[CH2:16][CH2:17][O:18][CH2:19][CH2:20]1>>[F:1][c:2]1[c:3](=[O:9])[nH:4][c:5](=[O:8])[n:6]([CH:13]2[CH2:12][CH2:11][CH2:10][O:14]2)[cH:7]1

Participants

4

Reactant 3

HCID 33855-FluorouracilHCID 312751,4-DioxaneHCID 709342,3-Dihydrofuran

Product 1

HCID 5386Tegafur

Sources & evidence

ORD record
ord-310bce648fc24a42989ad68efff783e5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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