Dichloromethane → 4-(4-(2,6-Difluorobenzyloxy)phenyl)-4-oxobutyric acid
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH2:8][C:9](=[O:10])[c:11]1[cH:12][cH:13][c:14]([O:17][CH2:18][c:19]2[c:20]([F:26])[cH:21][cH:22][cH:23][c:24]2[F:25])[cH:15][cH:16]1)=[O:27].[Cl:35][CH2:36][Cl:37].[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[O:5]=[C:6]([CH2:7][CH2:8][C:9](=[O:10])[c:11]1[cH:12][cH:13][c:14]([O:17][CH2:18][c:19]2[c:20]([F:26])[cH:21][cH:22][cH:23][c:24]2[F:25])[cH:15][cH:16]1)[OH:27]Participants
4
Sources & evidence
- ORD record
- ord-9a7575e635534d3eb49d69e4f34492c4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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