Hydrochloric Acid → 7-Chloro-5-[(2,3-difluorophenylmethyl)thio]-2-methoxythiazolo[4,5-d]pyrimidine
Reaction equation
[Br:1][c:2]1[s:3][c:4]2[c:5]([n:6][c:7]([S:11][CH2:12][c:13]3[c:14]([F:20])[c:15]([F:19])[cH:16][cH:17][cH:18]3)[n:8][c:9]2[Cl:10])[n:21]1.[CH3:25][OH:26].[ClH:24].[K+:23].[OH-:22]>>[c:2]1([O:22][CH3:25])[s:3][c:4]2[c:5]([n:6][c:7]([S:11][CH2:12][c:13]3[c:14]([F:20])[c:15]([F:19])[cH:16][cH:17][cH:18]3)[n:8][c:9]2[Cl:10])[n:21]1Participants
6
Sources & evidence
- ORD record
- ord-0dd7ae694df543efb7742eabc88eabad
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…