Hydrochloric Acid → 5-Acetylfuro(2,3-c)pyridine

HRID 957024Notes

Reaction equation

HRID 957024 reaction equation
[CH3:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[ClH:53].[Na+:55].[O:17]=[C:18]([c:19]1[cH:20][c:21]2[cH:22][cH:23][o:24][c:25]2[cH:26][n:27]1)[CH2:28][C:29]([O:30][CH2:31][CH3:32])=[O:33].[O:1]=[C:2]([CH2:3][C:4]([O:5][CH3:6])=[O:7])[c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[o:14][cH:15][cH:16]2.[O:34]=[C:35]([c:36]1[cH:37][c:38]2[cH:39][cH:40][o:41][c:42]2[cH:43][n:44]1)[CH2:45][C:46]([O:47][C:48]([CH3:49])([CH3:50])[CH3:51])=[O:52].[OH-:54]>>[O:1]=[C:2]([CH3:3])[c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[o:14][cH:15][cH:16]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 1140TolueneHCID 9859266Methyl beta-oxo-5-furo[2,3-c]pyridinepropionateHCID 18324176Ethyl beta-oxo-5-furo[2,3-c]pyridinepropionateHCID 18324178Tert-butyl beta-oxo-5-furo[2,3-c]pyridinepropionate

Product 1

HCID 97939025-Acetylfuro(2,3-c)pyridine

Sources & evidence

ORD record
ord-7a1d4cfe5d1147feb3c081f9a7a5715b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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