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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 957058Generated: October 27, 2026

Tetrahydrofuran → 4-[2-(Trimethylsilyl)ethynyl]pyridine-2-carbonitrile

https://huagongshe.com/reaction/957058

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant4-Bromo-2-cyanopyridineHCID 693283—
Product4-[2-(Trimethylsilyl)ethynyl]pyridine-2-carbonitrileHCID 45116446—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-2eb74ffe14a04795853b2eb195c5b94a
Source noteValidation data from https://doi.org/10.1039/C8SC04228D