Dichloromethane → 1,3-dihydro-3-acetoxy-3-(2-pyridinylmethyl)-1-(4-morpholinyl)-2H-indol-2-one

HRID 957068Notes

Reaction equation

HRID 957068 reaction equation
[CH3:25][C:26](=[O:27])[O:28][C:29](=[O:30])[CH3:31].[CH3:32][N:33]([CH3:34])[c:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1.[Cl:41][CH2:42][Cl:43].[OH:1][C:2]1([CH2:18][c:19]2[n:20][cH:21][cH:22][cH:23][cH:24]2)[C:3](=[O:17])[N:4]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21>>[O:1]([C:2]1([CH2:18][c:19]2[n:20][cH:21][cH:22][cH:23][cH:24]2)[C:3](=[O:17])[N:4]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21)[C:26]([CH3:25])=[O:27]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7918Acetic AnhydrideHCID 142844-(Dimethylamino)pyridineHCID 233539751,3-dihydro-3-hydroxy-1-(4-morpholinyl)-3-(2-pyridinyl methyl)-2H-indol-2-one

Product 1

HCID 233539811,3-dihydro-3-acetoxy-3-(2-pyridinylmethyl)-1-(4-morpholinyl)-2H-indol-2-one

Sources & evidence

ORD record
ord-26b4be228b404288bf44bd72c20ed3f9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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