Phosphorus oxychloride → 3-Benzenesulphonyl-7-chloro-5-(4-methyl-piperazin-1-ylmethyl)-2-methylsulphanyl-pyrazolo[1,5-a]pyrimidine
Reaction equation
[P:30]([Cl:31])([Cl:32])([Cl:33])=[O:34].[c:1]1([S:7](=[O:8])(=[O:9])[c:10]2[c:11]([S:28][CH3:29])[n:12][n:13]3[c:14]2[n:15][c:16]([CH2:20][N:21]2[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]2)[cH:17][c:18]3[OH:19])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[c:10]2[c:11]([S:28][CH3:29])[n:12][n:13]3[c:14]2[n:15][c:16]([CH2:20][N:21]2[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]2)[cH:17][c:18]3[Cl:32])[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-a34f7a2766f64a2588369d410b072c6e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…