Chloroform → 2-Benzylamino-4-(t-butyl)amino-3,5,6-trifluoropyridine

HRID 957235Notes

Reaction equation

HRID 957235 reaction equation
[C:8]([CH3:9])([CH3:10])([CH3:11])[NH:12][c:13]1[c:14]([F:22])[c:15]([F:21])[n:16][c:17]([F:20])[c:18]1[F:19].[CH3:1][N:2]1[CH2:3][CH2:4][CH2:5][C:6]1=[O:7].[CH:31]([Cl:32])([Cl:33])[Cl:34].[NH2:23][CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1>>[C:8]([CH3:9])([CH3:10])([CH3:11])[NH:12][c:13]1[c:14]([F:22])[c:15]([NH:23][CH2:24][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[n:16][c:17]([F:20])[c:18]1[F:19]

Participants

5

Reactant 4

HCID 6212ChloroformHCID 7504BenzylamineHCID 13387N-methyl-2-pyrrolidoneHCID 221211594-(t-Butylamino)-2,3,5,6-tetrafluoropyridine

Product 1

HCID 221212672-Benzylamino-4-(t-butyl)amino-3,5,6-trifluoropyridine

Sources & evidence

ORD record
ord-34b1f3cdf55041ee878f53d14689705a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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