Hydrochloric Acid → 4,4-Dimethyl-2-(4'hydroxymethylbiphenyl-2-yl)oxazoline

HRID 957428Notes

Reaction equation

HRID 957428 reaction equation
[CH3:1][C:2]1([CH3:27])[N:3]=[C:4]([c:7]2[c:8](-[c:13]3[cH:14][cH:15][c:16]([CH2:19][O:20][CH:21]4[CH2:22][CH2:23][CH2:24][CH2:25][O:26]4)[cH:17][cH:18]3)[cH:9][cH:10][cH:11][cH:12]2)[O:5][CH2:6]1.[CH3:34][OH:35].[ClH:28].[Na+:29].[OH:30][C:31](=[O:32])[O-:33]>>[CH3:1][C:2]1([CH3:27])[N:3]=[C:4]([c:7]2[c:8](-[c:13]3[cH:14][cH:15][c:16]([CH2:19][OH:20])[cH:17][cH:18]3)[cH:9][cH:10][cH:11][cH:12]2)[O:5][CH2:6]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ionHCID 153808764,4-Dimethyl-2-(4'-tetrahydropyranyloxymethylbiphenyl-2-yl)oxazoline

Product 1

HCID 110658764,4-Dimethyl-2-(4'hydroxymethylbiphenyl-2-yl)oxazoline

Sources & evidence

ORD record
ord-f828fb3e09974d008cce0e86b7fa8af4
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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