Dichloromethane → 4-[6-(5-Methanesulfonyl-2,3-dihydro-indol-1-yl)-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid pyrrolidin-3-yl ester
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([O:13][C:14](=[O:15])[N:16]2[CH2:17][CH2:18][CH:19]([O:22][c:23]3[n:24][cH:25][n:26][c:27]([N:29]4[CH2:30][CH2:31][c:32]5[cH:33][c:34]([S:38](=[O:39])(=[O:40])[CH3:41])[cH:35][cH:36][c:37]54)[cH:28]3)[CH2:20][CH2:21]2)[CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:49][CH2:50][Cl:51].[F:42][C:43]([F:44])([F:45])[C:46]([OH:47])=[O:48]>>[NH:8]1[CH2:9][CH:10]([O:13][C:14](=[O:15])[N:16]2[CH2:17][CH2:18][CH:19]([O:22][c:23]3[n:24][cH:25][n:26][c:27]([N:29]4[CH2:30][CH2:31][c:32]5[cH:33][c:34]([S:38](=[O:39])(=[O:40])[CH3:41])[cH:35][cH:36][c:37]54)[cH:28]3)[CH2:20][CH2:21]2)[CH2:11][CH2:12]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7082570e789943f3a4e9af2f7cfaae45
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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