Methanol → methyl 3-(7-hydroxy-1-oxoisoquinolin-2(1H)-yl)-4-methylbenzoate

HRID 957460Notes

Reaction equation

HRID 957460 reaction equation
[CH2:34]([Cl:35])[Cl:36].[CH3:32][OH:33].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[OH:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][n:8](-[c:13]3[cH:14][c:15]([C:16](=[O:17])[OH:18])[cH:19][cH:20][c:21]3[CH3:22])[c:9](=[O:12])[c:10]2[cH:11]1.[S:23]([Cl:24])([Cl:25])=[O:26]>>[OH:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][n:8](-[c:13]3[cH:14][c:15]([C:16](=[O:17])[O:18][CH3:28])[cH:19][cH:20][c:21]3[CH3:22])[c:9](=[O:12])[c:10]2[cH:11]1

Participants

6

Reactant 5

HCID 887MethanolHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 670185873-(7-hydroxy-1-oxo-1H-isoquinolin-2-yl)-4-methylbenzoic acid

Product 1

HCID 67018571methyl 3-(7-hydroxy-1-oxoisoquinolin-2(1H)-yl)-4-methylbenzoate

Sources & evidence

ORD record
ord-7e71076388a34630beccb7375fe226cf
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…