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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 957521Generated: October 29, 2026

Phosphorus oxychloride → 4-Chloro-2-chloromethyl-7-(3-trifluoromethyl-pyridin-2-yl)-quinazoline

https://huagongshe.com/reaction/957521

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
Reactant2-chloromethyl-7-(3-trifluoromethyl-pyridin-2-yl)-3H-quinazolin-4-oneHCID 135682066—
Product4-Chloro-2-chloromethyl-7-(3-trifluoromethyl-pyridin-2-yl)-quinazolineHCID 22030150—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-00fa39a5c0dd444b8c48c62e0b1905ef
Source noteValidation data from https://doi.org/10.1039/C8SC04228D