Bicarbonate Ion → tert-butyl 3-[(5,6-difluoro-1H-benzimidazole-2-carbonyl)-(2-methylpropyl)amino]-5-(morpholine-4-carbonyl)piperidine-1-carboxylate

HRID 957541Notes

Reaction equation

[C:42]([OH:43])(=[O:44])[O-:45].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:16][CH:17]([CH2:18][NH:19][CH:20]1[CH2:21][N:22]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:23][CH:24]([C:26](=[O:27])[N:28]2[CH2:29][CH2:30][O:31][CH2:32][CH2:33]2)[CH2:25]1)[CH3:41].[F:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([C:9]([Cl:10])([Cl:11])[Cl:12])[n:8]2)[cH:13][c:14]1[F:15].[Na+:46].[OH2:47]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([C:9]([N:19]([CH2:18][CH:17]([CH3:16])[CH3:41])[CH:20]3[CH2:21][N:22]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:23][CH:24]([C:26](=[O:27])[N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[CH2:25]3)=[O:43])[n:8]2)[cH:13][c:14]1[F:15]