Sodium ion → 2-{4-(1,3-benzodioxol-5-yl)-5-methoxy-3-[(methoxymethyl)(phenethylsulfonyl)amino]-1H-pyrazol-1-yl}ethyl Acetate

HRID 957821Notes

Reaction equation

HRID 957821 reaction equation
[Br:41][CH2:42][CH2:43][CH2:44][C:45]([O-:46])=[O:47].[C:34]([CH3:35])(=[O:36])[O:37][CH2:38][CH2:39][Br:40].[H-:1].[Na+:2].[O:3]1[CH2:4][O:5][c:6]2[c:7]1[cH:8][cH:9][c:10](-[c:12]1[c:13]([O:32][CH3:33])[n:14][nH:15][c:16]1[N:17]([S:18](=[O:19])(=[O:20])[CH2:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[CH2:29][O:30][CH3:31])[cH:11]2.[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1>>[O:3]1[CH2:4][O:5][c:6]2[c:7]1[cH:8][cH:9][c:10](-[c:12]1[c:13]([O:32][CH3:33])[n:14]([CH2:39][CH2:38][O:37][C:34]([CH3:35])=[O:36])[n:15][c:16]1[N:17]([S:18](=[O:19])(=[O:20])[CH2:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[CH2:29][O:30][CH3:31])[cH:11]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 135641-Acetoxy-2-bromoethaneHCID 166653HydrideHCID 69936583-BromomethylpropionateHCID 22282022N-[4-(1,3-benzodioxol-5-yl)-3-methoxy-1H-pyrazol-5-yl]-N-(methoxymethyl)-2-phenyl-1-ethanesulfonamide

Product 1

HCID 222819772-{4-(1,3-benzodioxol-5-yl)-5-methoxy-3-[(methoxymethyl)(phenethylsulfonyl)amino]-1H-pyrazol-1-yl}ethyl Acetate

Sources & evidence

ORD record
ord-b2047094f93c4b8889be1c2d6d50f33f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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