Hydrochloric Acid → 3'-(4-Ethoxyphenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazine

HRID 958002Notes

Reaction equation

HRID 958002 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][cH:17][n:18][c:19]2-[c:20]2[cH:21][cH:22][c:23]([O:26][CH2:27][CH3:28])[cH:24][cH:25]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:30]1[O:31][CH2:32][CH2:33][O:34][CH2:35]1.[Cl:36][CH2:37][Cl:38].[ClH:29]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][cH:17][n:18][c:19]2-[c:20]2[cH:21][cH:22][c:23]([O:26][CH2:27][CH3:28])[cH:24][cH:25]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 687387893'-(4-Ethoxyphenyl)-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carboxylic acid t-butyl ester

Product 1

HCID 685953423'-(4-Ethoxyphenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazine

Sources & evidence

ORD record
ord-a011d852bf40485aacf708fdeb47b4f3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…