Acetic Acid → Ethyl 4-chloro-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxylate
Reaction equation
[CH3:29][C:30](=[O:31])[OH:32].[Cl:21][N:22]1[C:23](=[O:24])[CH2:25][CH2:26][C:27]1=[O:28].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[n:12][o:13]2)[cH:7][cH:8]1)([F:19])[F:20]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([Cl:21])[c:11]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[n:12][o:13]2)[cH:7][cH:8]1)([F:19])[F:20]Participants
4
Sources & evidence
- ORD record
- ord-6c6bd188781a43a99f18004181935e40
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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