Dichloromethane → 1-Methanesulfonyl-piperidine-4-carboxylic acid [2-(2,4-dichloro-phenoxy)-phenyl]-amide

HRID 958215Notes

Reaction equation

HRID 958215 reaction equation
[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][S:33]([Cl:34])(=[O:35])=[O:36].[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([NH:11][C:12](=[O:13])[CH:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[cH:7][cH:8][cH:9][cH:10]2)[cH:20][cH:21][c:22]([Cl:24])[cH:23]1.[Cl:37][CH2:38][Cl:39]>>[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([NH:11][C:12](=[O:13])[CH:14]3[CH2:15][CH2:16][N:17]([S:33]([CH3:32])(=[O:35])=[O:36])[CH2:18][CH2:19]3)[cH:7][cH:8][cH:9][cH:10]2)[cH:20][cH:21][c:22]([Cl:24])[cH:23]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 57550293N-[2-(2,4-Dichlorophenoxy)phenyl]piperidine-4-carboxamide

Product 1

HCID 159530461-Methanesulfonyl-piperidine-4-carboxylic acid [2-(2,4-dichloro-phenoxy)-phenyl]-amide

Sources & evidence

ORD record
ord-dfa6b93f99884c2a8923ee4a149111d7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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