Bromide ion → 1-(3-Bromopropoxy)-4-fluorobenzene

HRID 958223Notes

Reaction equation

HRID 958223 reaction equation
[Br-:19].[Br:9][CH2:10][CH2:11][CH2:12][Br:13].[CH2:16]([Cl:17])[Cl:18].[CH2:20]([N+:21]([CH2:22][CH2:23][CH2:24][CH3:25])([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:30][CH2:31][CH2:32][CH3:33])[CH2:34][CH2:35][CH3:36].[F:1][c:2]1[cH:3][cH:4][c:5]([OH:8])[cH:6][cH:7]1.[Na+:15].[OH-:14].[OH2:37]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH2:12][CH2:11][CH2:10][Br:9])[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 259Bromide ionHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 80011,3-DibromopropaneHCID 97324-FluorophenolHCID 16028Tetrabutylammonium

Product 1

HCID 2600041-(3-Bromopropoxy)-4-fluorobenzene

Sources & evidence

ORD record
ord-96e3e8e788974ba8abf09d959ef02585
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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