Methanol → 1-Isopropyl-5-(3'-methanesulfonyl-biphenyl-3-yl)-imidazolidin-2-one
Reaction equation
[CH3:36][OH:37].[Mg:35].[c:1]1([S:2](=[O:3])(=[O:4])[N:10]2[C:11](=[O:34])[N:12]([CH:31]([CH3:32])[CH3:33])[CH:13]([c:15]3[cH:16][c:17](-[c:21]4[cH:22][c:23]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:24][cH:25][cH:26]4)[cH:18][cH:19][cH:20]3)[CH2:14]2)[cH:5][cH:6][cH:7][cH:8][cH:9]1>>[NH:10]1[C:11](=[O:34])[N:12]([CH:31]([CH3:32])[CH3:33])[CH:13]([c:15]2[cH:16][c:17](-[c:21]3[cH:22][c:23]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:24][cH:25][cH:26]3)[cH:18][cH:19][cH:20]2)[CH2:14]1Participants
4
Sources & evidence
- ORD record
- ord-8c8b07358de1496a84bf31c782ed3880
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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