Imidazole → 2-Imidazol-1-yl-4-(4-methoxy-benzylamino)-thieno[3,2-c]pyridine-7-carbonitrile

HRID 958302Notes

Reaction equation

HRID 958302 reaction equation
[C:6](=[O:7])([O-:8])[O-:9].[Cs+:10].[Cs+:11].[Cu:34][I:35].[I:12][c:13]1[cH:14][c:15]2[c:16]([NH:24][CH2:25][c:26]3[cH:27][cH:28][c:29]([O:32][CH3:33])[cH:30][cH:31]3)[n:17][cH:18][c:19]([C:22]#[N:23])[c:20]2[s:21]1.[O:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1.[nH:1]1[cH:2][n:3][cH:4][cH:5]1>>[n:1]1(-[c:13]2[cH:14][c:15]3[c:16]([NH:24][CH2:25][c:26]4[cH:27][cH:28][c:29]([O:32][CH3:33])[cH:30][cH:31]4)[n:17][cH:18][c:19]([C:22]#[N:23])[c:20]3[s:21]2)[cH:2][n:3][cH:4][cH:5]1

Participants

7

Reactant 6

HCID 795ImidazoleHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 18446524HCID 18446524, compound

Product 1

HCID 184465232-Imidazol-1-yl-4-(4-methoxy-benzylamino)-thieno[3,2-c]pyridine-7-carbonitrile

Sources & evidence

ORD record
ord-cbc9cfc926dc41029c4ed5720c36de45
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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