Dimethylformamide → 6,7-Dimethyl-1-(6-methyl-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester
Reaction equation
[Br:19][CH2:20][c:21]1[n:22][c:23]([CH3:27])[cH:24][cH:25][cH:26]1.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][nH:8][c:9]2[n:10][c:11]([CH3:18])[c:12]([CH3:17])[cH:13][c:14]2[c:15]1=[O:16].[CH3:28][N:29]([CH3:30])[CH:31]=[O:32]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8]([CH2:20][c:21]2[n:22][c:23]([CH3:27])[cH:24][cH:25][cH:26]2)[c:9]2[n:10][c:11]([CH3:18])[c:12]([CH3:17])[cH:13][c:14]2[c:15]1=[O:16]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-bd32e9b7ad6f483ca395776d0a5e5175
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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