Pyridine → 2-[7-chloro-1-(2,2-dimethylpropyl)-5-naphthalen-1-yl-2-oxo-5H-4,1-benzothiazepin-3-yl]acetonitrile
Reaction equation
[Cl:14][c:15]1[cH:16][cH:17][c:18]2[c:19]([cH:45]1)[CH:20]([c:35]1[cH:36][cH:37][cH:38][c:39]3[cH:40][cH:41][cH:42][cH:43][c:44]13)[S:21][CH:22]([CH2:31][C:32](=[O:33])[NH2:34])[C:23](=[O:30])[N:24]2[CH2:25][C:26]([CH3:27])([CH3:28])[CH3:29].[F:1][C:2]([F:3])([F:4])[C:5]([O:6][C:7](=[O:8])[C:9]([F:10])([F:11])[F:12])=[O:13].[cH:46]1[cH:47][cH:48][n:49][cH:50][cH:51]1>>[Cl:14][c:15]1[cH:16][cH:17][c:18]2[c:19]([cH:45]1)[CH:20]([c:35]1[cH:36][cH:37][cH:38][c:39]3[cH:40][cH:41][cH:42][cH:43][c:44]13)[S:21][CH:22]([CH2:31][C:32]#[N:34])[C:23](=[O:30])[N:24]2[CH2:25][C:26]([CH3:27])([CH3:28])[CH3:29]Participants
4
Sources & evidence
- ORD record
- ord-8da86cffffd74ce280b7f2ed61200a8a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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