Dichloromethane → (3-Nitro-5-(trifluoromethyl)phenyl)(thiomorpholino)-methanone

HRID 958547Notes

Reaction equation

HRID 958547 reaction equation
[CH2:26]1[CH2:27][S:28][CH2:29][CH2:30][NH:31]1.[CH:17]([N:18]([CH2:19][CH3:20])[CH:21]([CH3:22])[CH3:23])([CH3:24])[CH3:25].[Cl:36][CH2:37][Cl:38].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][c:6]([C:7](=[O:8])[OH:9])[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]1.[S:32]([Cl:33])([Cl:34])=[O:35]>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][c:6]([C:7](=[O:9])[N:31]2[CH2:26][CH2:27][S:28][CH2:29][CH2:30]2)[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 67164ThiomorpholineHCID 81531DiisopropylethylamineHCID 6166023-Nitro-5-(trifluoromethyl)benzoic acid

Product 1

HCID 66970321(3-Nitro-5-(trifluoromethyl)phenyl)(thiomorpholino)-methanone

Sources & evidence

ORD record
ord-6983ae4904904fa383158ee457f0fc32
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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