Dimethylformamide → 1-{[5-(Chloromethyl)pyrazin-2-yl]methyl}-3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methylpyridin-2(1H)-one
Reaction equation
[Br:6][c:7]1[c:8](=[O:33])[n:9]([CH2:24][c:25]2[n:26][cH:27][c:28]([CH2:31][OH:32])[n:29][cH:30]2)[c:10]([CH3:23])[cH:11][c:12]1[O:13][CH2:14][c:15]1[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]1.[Cl:34][CH2:35][Cl:36].[O:1]=[CH:2][N:3]([CH3:4])[CH3:5]>>[Br:6][c:7]1[c:8](=[O:33])[n:9]([CH2:24][c:25]2[n:26][cH:27][c:28]([CH2:31][Cl:34])[n:29][cH:30]2)[c:10]([CH3:23])[cH:11][c:12]1[O:13][CH2:14][c:15]1[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-67d60ffed03b4a119beaa7779a2bd5c8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…