Dichloromethane → Methyl 4-amino-2-(trifluoromethyl)nicotinate
Reaction equation
[Cl:19][CH2:20][Cl:21].[IH:1].[N:2](=[N+:3]=[N-:4])[c:5]1[cH:6][cH:7][n:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]1[C:11](=[O:12])[O:13][CH3:14]>>[NH2:2][c:5]1[cH:6][cH:7][n:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]1[C:11](=[O:12])[O:13][CH3:14]Participants
4
Sources & evidence
- ORD record
- ord-78c510616b1944939751fd47e05649cd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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