Dichloromethane → N-(1,4-dioxa-spiro[4.5]dec-8-yl)-4-fluoro-N-methyl-benzenesulfonamide

HRID 958775Notes

Reaction equation

HRID 958775 reaction equation
[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[Cl:32][CH2:33][Cl:34].[F:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][CH:8]([NH:11][CH3:12])[CH2:9][CH2:10]2.[S:20](=[O:21])(=[O:22])([Cl:23])[Cl:24]>>[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][CH:8]([N:11]([CH3:12])[S:20](=[O:21])(=[O:22])[c:29]1[cH:28][cH:27][c:26]([F:25])[cH:31][cH:30]1)[CH2:9][CH2:10]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10008FluorobenzeneHCID 24648Sulfuryl chlorideHCID 16786570N-methyl-1,4-dioxaspiro(4.5)decan-8-amine

Product 1

HCID 67435736N-(1,4-dioxa-spiro[4.5]dec-8-yl)-4-fluoro-N-methyl-benzenesulfonamide

Sources & evidence

ORD record
ord-6ebbf435707f407cad49d715883e875b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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