Dichloromethane → 1-(4-(2-(2-Aminopyridin-4-yl)propoxy)naphthalen-1-yl)-3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)urea
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7](-[c:42]2[cH:43][cH:44][c:45]([CH3:48])[cH:46][cH:47]2)[c:8]([NH:10][C:11]([NH:12][c:13]2[cH:14][cH:15][c:16]([O:23][CH2:24][CH:25]([CH3:26])[c:27]3[cH:28][c:29]([NH:33][C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[n:30][cH:31][cH:32]3)[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)=[O:41])[cH:9]1.[Cl:56][CH2:57][Cl:58].[F:49][C:50]([F:51])([F:52])[C:53]([OH:54])=[O:55]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7](-[c:42]2[cH:43][cH:44][c:45]([CH3:48])[cH:46][cH:47]2)[c:8]([NH:10][C:11]([NH:12][c:13]2[cH:14][cH:15][c:16]([O:23][CH2:24][CH:25]([CH3:26])[c:27]3[cH:28][c:29]([NH2:33])[n:30][cH:31][cH:32]3)[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)=[O:41])[cH:9]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-dee4e3ff9acf4742901765ff29e2938a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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