Chloride → tert-Butyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-5-carboxylate

HRID 958933Notes

Reaction equation

HRID 958933 reaction equation
[C:43](=[O:44])([O-:45])[OH:46].[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[c:15]1[cH:16][c:17]2[cH:18][cH:19][n:20]([CH2:24][CH:25]([CH2:26][O:27][c:28]3[cH:29][cH:30][c:31]([CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[cH:32][cH:33]3)[OH:42])[c:21]2[cH:22][cH:23]1.[CH3:1][C:2]([O:3][C:4](=[O:5])[CH3:6])=[O:7].[CH3:50][S:51]([CH3:52])=[O:53].[Cl-:48].[Na+:47].[Na+:49]>>[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[c:15]1[cH:16][c:17]2[cH:18][cH:19][n:20]([CH2:24][C:25]([CH2:26][O:27][c:28]3[cH:29][cH:30][c:31]([CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[cH:32][cH:33]3)=[O:42])[c:21]2[cH:22][cH:23]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 679Dimethyl SulfoxideHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 7918Acetic AnhydrideHCID 12992906tert-Butyl-1-[2-hydroxy-3-(4-octylphenoxy)propyl]indole-5-carboxylate

Product 1

HCID 12992907tert-Butyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-5-carboxylate

Sources & evidence

ORD record
ord-ddcabb31d79443daaa5fc49181dcd7fe
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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