Sodium ion → Methyl 2-chloronicotinate

HRID 959049Notes

Reaction equation

HRID 959049 reaction equation
[CH3:15][I:16].[CH3:17][N:18]([CH3:19])[CH:20]=[O:21].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][n:10]1.[H-:11].[H:13][H:14].[Na+:12]>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:15])[cH:7][cH:8][cH:9][n:10]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 762582-Chloronicotinic acidHCID 166653HydrideHCID 178418361HCID 178418361, compound

Product 1

HCID 819931Methyl 2-chloronicotinate

Sources & evidence

ORD record
ord-335d7847cbfd446e9bf44ba634684ce5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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