Tetrahydrofuran → tert-butyl N-[4-[[5-bromo-6-(pyridin-4-ylmethylamino)-3-pyridinyl]sulfonyl]-5-methylsulfanylthiophene-2-carboximidoyl]carbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8](=[NH:9])[c:10]1[s:11][c:12]([S:26][CH3:27])[c:13]([S:15](=[O:16])(=[O:17])[c:18]2[cH:19][n:20][c:21]([Cl:25])[c:22]([Br:24])[cH:23]2)[cH:14]1)=[O:28].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[NH2:29][CH2:30][c:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8](=[NH:9])[c:10]1[s:11][c:12]([S:26][CH3:27])[c:13]([S:15](=[O:16])(=[O:17])[c:18]2[cH:19][n:20][c:21]([NH:29][CH2:30][c:31]3[cH:32][cH:33][n:34][cH:35][cH:36]3)[c:22]([Br:24])[cH:23]2)[cH:14]1)=[O:28]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-45b654ff9fbd49ac8fbe4ed4a0cd3d6f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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