Acetonitrile → Ethyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

HRID 959093Notes

Reaction equation

HRID 959093 reaction equation
[Br:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[C:15](=[O:16])([O-:17])[O-:18].[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8]([Br:13])[c:9]([OH:12])[cH:10][cH:11]1)=[O:14].[CH3:29][C:30]#[N:31].[Cs+:19].[Cs+:20]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8]([Br:13])[c:9]([O:12][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:10][cH:11]1)=[O:14]

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 7498Benzyl BromideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 18620106Ethyl 2-(3-bromo-4-hydroxyphenyl)acetate

Product 1

HCID 18620085Ethyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

Sources & evidence

ORD record
ord-f1e56254d71743b48c7dd21792556e4e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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