Ethanol → Tert-butyl 2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carboxylate
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]2([c:39]3[cH:40][cH:41][cH:42][cH:43][cH:44]3)[CH:10]([O:23][CH2:24][c:25]3[cH:26][c:27]([C:35]([F:36])([F:37])[F:38])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]3)[CH2:11][CH2:12][CH:13]1[CH:14]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:15]2.[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[CH3:51][CH2:52][OH:53]>>[NH:8]1[C:9]2([c:39]3[cH:40][cH:41][cH:42][cH:43][cH:44]3)[CH:10]([O:23][CH2:24][c:25]3[cH:26][c:27]([C:35]([F:36])([F:37])[F:38])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]3)[CH2:11][CH2:12][CH:13]1[CH:14]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:15]2Participants
4
Sources & evidence
- ORD record
- ord-a02acb6597af4b96a64b6052188a4e9c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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