Dichloromethane → 4-Benzamido-1-(2-benzoyloxyethyl)piperidine

HRID 959289Notes

Reaction equation

HRID 959289 reaction equation
[C:10]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)(=[O:17])[NH:18][CH:19]1[CH2:20][CH2:21][N:22]([CH2:25][CH2:26][OH:27])[CH2:23][CH2:24]1.[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[Cl:9].[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[Cl:35][CH2:36][Cl:37]>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[O:27][CH2:26][CH2:25][N:22]1[CH2:21][CH2:20][CH:19]([NH:18][C:10]([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)=[O:17])[CH2:24][CH2:23]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7412Benzoyl chlorideHCID 8471TriethylamineHCID 203151761-(2-Hydroxyethyl)-4-benzamidopiperidine

Product 1

HCID 203151754-Benzamido-1-(2-benzoyloxyethyl)piperidine

Sources & evidence

ORD record
ord-c1aac31ca45a432494ad08a71953e567
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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