Dichloromethane → 4-hydroxy-5-(2-isopropylphenyl)sulfanyl-2,2-diphenyl-3H-pyran-6-one

HRID 959368Notes

Reaction equation

HRID 959368 reaction equation
[Br:1][C:2]1=[C:7]([OH:8])[CH2:6][C:5]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[O:4][C:3]1=[O:21].[CH2:32]1[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]1.[CH:22]([CH3:23])([CH3:24])[c:25]1[c:26]([SH:31])[cH:27][cH:28][cH:29][cH:30]1.[Cl:38][CH2:39][Cl:40]>>[C:2]1([S:31][c:26]2[c:25]([CH:22]([CH3:23])[CH3:24])[cH:30][cH:29][cH:28][cH:27]2)=[C:7]([OH:8])[CH2:6][C:5]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[O:4][C:3]1=[O:21]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8082PiperidineHCID 96003Benzenethiol, 2-(1-methylethyl)-HCID 547215603-bromo-5,6-dihydro-4-hydroxy-6,6-diphenyl-2H-pyran-2-one

Product 1

HCID 546890124-hydroxy-5-(2-isopropylphenyl)sulfanyl-2,2-diphenyl-3H-pyran-6-one

Sources & evidence

ORD record
ord-ce42173aa9a941769d11ba8a5694fa41
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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