Methanol → tert-Butyl 4-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate

HRID 959370Notes

Reaction equation

HRID 959370 reaction equation
[C:23]([O:24][CH2:25][CH3:26])(=[O:27])[CH3:28].[CH3:1][O:2][C:3]([CH:4]=[C:5]1[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:9][CH2:10]1)=[O:18].[CH3:21][OH:22].[H:19][H:20]>>[CH3:1][O:2][C:3]([CH2:4][CH:5]1[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:9][CH2:10]1)=[O:18]

Participants

5

Reactant 4

HCID 887MethanolHCID 8857Ethyl AcetateHCID 10377658Tert-butyl 4-(2-methoxy-2-oxoethylidene)piperidine-1-carboxylateHCID 178418361HCID 178418361, compound

Product 1

HCID 1514280tert-Butyl 4-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-a915e79a08784e4981f70490d4b97d38
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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