Phosphorus oxychloride → 3-Chloromethyl-1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methylpiperidine
Reaction equation
[O:6]1[CH:7]([CH2:16][N:17]2[CH2:18][C:19]([CH3:23])([CH2:24][OH:25])[CH2:20][CH2:21][CH2:22]2)[CH2:8][O:9][c:10]2[c:11]1[cH:12][cH:13][cH:14][cH:15]2.[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5]>>[Cl:3][CH2:24][C:19]1([CH3:23])[CH2:18][N:17]([CH2:16][CH:7]2[O:6][c:11]3[c:10]([cH:15][cH:14][cH:13][cH:12]3)[O:9][CH2:8]2)[CH2:22][CH2:21][CH2:20]1Participants
3
Sources & evidence
- ORD record
- ord-1f61c32653b0456382471599fd394816
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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