Potassium Cation → 8-tert-Butyl-2-(4-tert-butylpiperidinomethyl)-1,4-dioxaspiro[4,5]decane

HRID 959533Notes

Reaction equation

HRID 959533 reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[CH:15]1[CH2:16][CH2:17][C:18]2([O:19][CH2:20][CH:21]([CH2:23][Br:24])[O:22]2)[CH2:25][CH2:26]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[CH:5]1[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]1.[C:27](=[O:28])([O-:29])[O-:30].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[K+:31].[K+:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[CH:5]1[CH2:6][CH2:7][N:8]([CH2:23][CH:21]2[CH2:20][O:19][C:18]3([CH2:17][CH2:16][CH:15]([C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:26][CH2:25]3)[O:22]2)[CH2:9][CH2:10]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 74661Piperidine, 4-(1,1-dimethylethyl)-HCID 14837662HCID 14837662, compound

Product 1

HCID 148376638-tert-Butyl-2-(4-tert-butylpiperidinomethyl)-1,4-dioxaspiro[4,5]decane

Sources & evidence

ORD record
ord-7f5d82faeeaf4fc9a500d0b0d357cbd2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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