Phosphorus oxychloride → 7-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carbonitrile
Reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][O:30][CH2:31]1.[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:20])[N:9]([CH3:19])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1[C:16](=[O:17])[NH2:18].[P:21]([Cl:22])([Cl:23])([Cl:24])=[O:25]>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:20])[N:9]([CH3:19])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1[C:16]#[N:18]Participants
4
Sources & evidence
- ORD record
- ord-afedf91a3ce24d57ad701de8a72e8dc3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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