Methanol → (2-methoxy-quinazolin-4-yl)-(4-methoxyphenyl)-methylamine

HRID 959753Notes

Reaction equation

HRID 959753 reaction equation
[CH2:27]([O:28][C:29](=[O:30])[CH3:31])[CH3:32].[CH3:22][O-:23].[CH3:25][OH:26].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([N:12]([CH3:13])[c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[n:11]1.[Na+:24]>>[c:2]1([O:23][CH3:22])[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([N:12]([CH3:13])[c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[n:11]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 8857Ethyl AcetateHCID 3826051MethoxideHCID 117381122-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine

Product 1

HCID 11437885(2-methoxy-quinazolin-4-yl)-(4-methoxyphenyl)-methylamine

Sources & evidence

ORD record
ord-63c385ebf20b4d10be80404bf3146fff
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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