Isopropanol → 6-[4-[2-[3-(2-cyanophenoxy)-2-hydroxypropylamino]-2-methylpropyl-amino]phenyl]-4,5-dihydro-3(2H)-pyridazinone
Reaction equation
[C:20](#[N:21])[c:22]1[c:23]([O:24][CH2:25][CH:26]2[CH2:27][O:28]2)[cH:29][cH:30][cH:31][cH:32]1.[CH:33]([OH:34])([CH3:35])[CH3:36].[NH2:1][C:2]([CH2:3][NH:4][c:5]1[cH:6][cH:7][c:8]([C:11]2=[N:16][NH:15][C:14](=[O:17])[CH2:13][CH2:12]2)[cH:9][cH:10]1)([CH3:18])[CH3:19]>>[NH:1]([C:2]([CH2:3][NH:4][c:5]1[cH:6][cH:7][c:8]([C:11]2=[N:16][NH:15][C:14](=[O:17])[CH2:13][CH2:12]2)[cH:9][cH:10]1)([CH3:18])[CH3:19])[CH2:27][CH:26]([CH2:25][O:24][c:23]1[c:22]([C:20]#[N:21])[cH:32][cH:31][cH:30][cH:29]1)[OH:28]Participants
4
Sources & evidence
- ORD record
- ord-6f3fe063bc9940eb92c947c8130642bb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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